For the first time, a dozen Mediterranean countries, several cooperation and research actors participated in the 2nd independent Mediterranean Dialogue of the United Nations Summit on Food Systems. A new step to advance on common ambitions for the region. Organised by the CIHEAM, the FAO, the UfM, the One Planet network and the Prima Foundation for more sustainable and inclusive food systems in the Mediterranean region, this 2nd Dialogue follows the first one held on 27 April 2021. A common vision for the future and ambitious programmes emerged from the debates, particularly in the framework of the SFS-MED platform. The conclusions of this 2nd Dialogue will enrich the preparatory process for the United Nations Summit to be held in New York in September 2021 and the Programme of the 3rd World Conference on the Mediterranean Diet and Sustainable Food Systems in the Mediterranean scheduled for 2022.